Serpina3g CLIA Kit for Mouse(Mus musculus) | EIAab.comSerpina3g CLIA Kit for Mouse(Mus musculus)

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Serpina3g (Gene name),

Serine protease inhibitor A3G (Protein name ), SPA3G_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Serpina3g(Spi2A);

Protein name:

Serine protease inhibitor A3G(Serpin A3G);

Alternative:

Serine protease inhibitor 2A(Serpin 2A);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

N/A

Function:

Serine and cysteine protease inhibitor. Can inhibit lysosomal papain-like proteases including the cathepsins B, G, H, K, L and V. Ineffective against elastase, granzyme A, granzyme B, or caspases 3, 8 or 9. Inhibition of cytoplasmic cathepsin B following release from the lysosome may protect cells from apoptosis. This may facilitate the survival of progenitor T-cells and the subsequent development of long term memory CD8 T-cells.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

440

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

440:

MAKVTNPERS | MNFPNGEGAS | SQRLESKRLC | FGDPLCLIGQ |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.312628

KEGG:

mmu:20715

STRING:

10090.ENSMUSP00000041250

Pfam:

PF00079

SMR:

Q5I2A0

String:

Q5I2A0

Uniprot:

Q5I2A0

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ELISA Kit for Mouse Serpin A3G

Cat.:

E8852m

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Mouse Serpin A3G

Cat.:

U8852m

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Mouse Serpin A3G

Cat.:

P8852Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Serpin A3G

Protein for Mouse Serpin A3G

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

Liu N. , Ashton-Rickardt P.G. , Xia G.
Submitted (2004-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 91-440
strain: FVB/N.
tissue: Mammary gland.
3.

"Identification of a serpin specifically expressed in multipotent and bipotent hematopoietic progenitor cells and in activated T cells."
Hampson I.N. , Hampson L. , Pinkoski M. , Cross M. , Heyworth C.M. , Bleackley R.C. , Atkinson E. , Dexter T.M.
Blood89:108-118(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
4.

"From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs."
Terskikh A.V. , Easterday M.C. , Li L. , Hood L. , Kornblum H.I. , Geschwind D.H. , Weissman I.L.
Proc. Natl. Acad. Sci. U.S.A.98:7934-7939(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
5.

"Murine serpin 2A is a redox-sensitive intracellular protein."
Morris E.C. , Dafforn T.R. , Forsyth S.L. , Missen M.A. , Horvath A.J. , Hampson L. , Hampson I.N. , Currie G. , Carrell R.W. , Coughlin P.B.
Biochem. J.371:165-173(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
6.

"NF-kappaB protects from the lysosomal pathway of cell death."
Liu N. , Raja S.M. , Zazzeroni F. , Metkar S.S. , Shah R. , Zhang M. , Wang Y. , Broemme D. , Russin W.A. , Lee J.C. , Peter M.E. , Froelich C.J. , Franzoso G. , Ashton-Rickardt P.G.
EMBO J.22:5313-5322(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION
strain: C57BL/6.
7.

"A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins."
Forsyth S. , Horvath A. , Coughlin P.
Genomics81:336-345(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE FAMILY;NOMENCLATURE
8.

"Serine protease inhibitor 2A inhibits caspase-independent cell death."
Liu N. , Wang Y. , Ashton-Rickardt P.G.
FEBS Lett.569:49-53(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
strain: C57BL/6.
9.

"Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus."
Horvath A.J. , Forsyth S.L. , Coughlin P.B.
J. Mol. Evol.59:488-497(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;REGION RCL
10.

"Serine protease inhibitor 2A is a protective factor for memory T cell development."
Liu N. , Phillips T. , Zhang M. , Wang Y. , Opferman J.T. , Shah R. , Ashton-Rickardt P.G.
Nat. Immunol.5:919-926(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DEVELOPMENTAL STAGE
strain: C57BL/6.

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